Case report: end stage renal disease in a chronic kidney patient on warfarin therapy Relato de caso: Insuficiência renal crônica estádio 5 D em paciente com doença renal crônica medicado com varfarina

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dc.contributor.authorBento C.P.
dc.contributor.authorSoares M.
dc.contributor.authorMolin C.
dc.contributor.authorMartins L.
dc.contributor.authorMartins J.
dc.contributor.authorMazza M.
dc.contributor.authorRiella M.
dc.date.accessioned2024-03-13T00:57:24Z
dc.date.available2024-03-13T00:57:24Z
dc.date.issued2015
dc.description.abstractBACKGROUND: Warfarin therapy can provoke severe hematuria and acute kidney injury with the presence of occlusive red blood cell casts. These findings are compatible with a recently described disease entity, warfarin related nephropathy, which adversely affects renal and patient outcome.CASE REPORT: We report a 74-year-old man with chronic kidney disease stage 3 A, who developed a decline in glomerular filtration rate (GFR) after the initiation of warfarin therapy due to of atrial fibrillation. The diagnosis could be confirmed by renal histology which showed occlusion of renal tubules by red blood cells and casts consistent with this diagnosis. The patient did not recover the GFR and started renal replacement therapy in June (fourteen months after starting warfarin) 2014.DISCUSSION: The aim of the present report is to alert for this drug recognized complication and reinforce the need of carefully motorization of kidney function and coagulation parameters in patients treated with warfarin. The pathogenesis and outcome of warfarin-related nephropathy is also discussed here.
dc.description.firstpage275
dc.description.issuenumber2
dc.description.lastpage278
dc.description.volume37
dc.identifier.doi10.5935/0101-2800.20150043
dc.identifier.issn2175-8239
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36209
dc.relation.ispartofJornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
dc.rightsAcesso Aberto
dc.titleCase report: end stage renal disease in a chronic kidney patient on warfarin therapy Relato de caso: Insuficiência renal crônica estádio 5 D em paciente com doença renal crônica medicado com varfarina
dc.typeArtigo
local.scopus.citations0
local.scopus.eid2-s2.0-85021849291
local.scopus.subjectAged
local.scopus.subjectAnticoagulants
local.scopus.subjectAtrial Fibrillation
local.scopus.subjectHumans
local.scopus.subjectKidney Failure, Chronic
local.scopus.subjectMale
local.scopus.subjectRenal Insufficiency, Chronic
local.scopus.subjectWarfarin
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85021849291&origin=inward
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