A model of intelligent controller for hypothyroidism treatment

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dc.contributor.authorMartins L.G.A.
dc.contributor.authorMonteiro L.H.A.
dc.date.accessioned2024-03-13T01:30:39Z
dc.date.available2024-03-13T01:30:39Z
dc.date.issued2010
dc.description.abstractHypothyroidism results from an insufficiency either in the production or/and in the action of the thyroid hormones. Most of the patients in hypothyroidism state must adopt hormonal replacement therapy for all their lives. An intelligent controller model for supplying therapeutic drugs to primary hypothyroidism patients, without the thyroid gland, is investigated in this work. Two multilayer perceptron neural networks are used to predict the concentrations of the hormones TSH and T4 in the blood. The controller, based on a set of production rules, uses these forecasts and the current concentrations of such hormones for calculating the necessary drug dosage to be released. Beyond the controller maintaining such concentrations inside regularity bands, it is also able of preventing abrupt changes on the time evolution of these concentrations. © 2010 IEEE.
dc.description.firstpage472
dc.description.lastpage479
dc.identifier.doi10.1109/CIT.2010.106
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37136
dc.relation.ispartofProceedings - 10th IEEE International Conference on Computer and Information Technology, CIT-2010, 7th IEEE International Conference on Embedded Software and Systems, ICESS-2010, ScalCom-2010
dc.rightsAcesso Restrito
dc.subject.otherlanguageIntelligent control
dc.subject.otherlanguageNeural networks
dc.subject.otherlanguageProduction rules
dc.subject.otherlanguageThyroid hormones
dc.titleA model of intelligent controller for hypothyroidism treatment
dc.typeArtigo de evento
local.scopus.citations1
local.scopus.eid2-s2.0-78249240097
local.scopus.subjectAbrupt change
local.scopus.subjectCurrent concentration
local.scopus.subjectHormonal replacement therapies
local.scopus.subjectIntelligent controllers
local.scopus.subjectMulti-layer perceptron neural networks
local.scopus.subjectProduction rules
local.scopus.subjectTherapeutic drugs
local.scopus.subjectThyroid glands
local.scopus.subjectThyroid hormones
local.scopus.subjectTime evolutions
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78249240097&origin=inward
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