From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital

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dc.contributor.authorda Silva M.R.T.
dc.contributor.authorCosta A.P.
dc.contributor.authorda Luz A.A.
dc.contributor.authorPelaio C.H.
dc.contributor.authorCruz F.B.
dc.contributor.authorSteil G.F.
dc.contributor.authorGiamberardino H.I.G.
dc.contributor.authorPrando C.
dc.date.accessioned2024-09-01T06:18:39Z
dc.date.available2024-09-01T06:18:39Z
dc.date.issued2023
dc.description.abstract© 2023 by the authors.Background: The coronavirus disease 2019 (COVID-19) pandemic began in Brazil on 26 February 2020. By 6 May 2023, 37.4 million cases had been confirmed, causing 701 thousand deaths in the country. We aimed to describe the epidemiological profile and clinical development of COVID-19 cases among the employees of a health institution, from acute infection to long COVID. Methods: This was a longitudinal study using a retrospective and prospective approach via questionnaires referring to epidemiological investigation, which was the inclusion criteria, and about long-term symptoms. Results: A total of 809 employees were detected with SARS-CoV-2 infection via RT-PCR, 466 of them answered the epidemiological investigation, and 101 completed the Long COVID Symptom Questionnaire. The most commonly affected employees were women (88.6%) working in patient care (68.6%). Headache, myalgia, cough, odynophagia, and runny nose were the most frequent symptoms. Only three employees (0.6%) required hospitalization, while the other employees required outpatient management due to mild symptoms. We identified 19 (4.1%) cases of reinfection, and 42 (41.6%) employees reported long-term symptoms, such as myalgia, dyspnea, and headache. Conclusions: Although most cases were mild with good outcomes, long COVID cases identified are noteworthy, as these symptoms may impact quality of life even months after SARS-CoV-2 infection.
dc.description.issuenumber13
dc.description.volume12
dc.identifier.doi10.3390/jcm12134325
dc.identifier.issnNone
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/39296
dc.relation.ispartofJournal of Clinical Medicine
dc.rightsAcesso Aberto
dc.subject.otherlanguageCOVID-19
dc.subject.otherlanguagehealthcare professionals
dc.subject.otherlanguagelong COVID
dc.subject.otherlanguageoccupational medicine
dc.subject.otherlanguagereinfection
dc.titleFrom Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital
dc.typeArtigo
local.scopus.citations3
local.scopus.eid2-s2.0-85165165787
local.scopus.updated2025-04-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85165165787&origin=inward
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