Naturally acquired antibodies to tetanus toxin in humans and animals from the Galapagos Islands

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dc.contributor.authorVeronesi R.
dc.contributor.authorBizzini B.
dc.contributor.authorFocaccia R.
dc.contributor.authorCoscina A.L.
dc.contributor.authorMazza C.C.
dc.contributor.authorFocaccia M.T.
dc.contributor.authorCarraro F.
dc.contributor.authorHonningman M.N.
dc.date.accessioned2024-03-13T01:47:49Z
dc.date.available2024-03-13T01:47:49Z
dc.date.issued1983
dc.description.abstractA serologic survey using a highly sensitive enzyme-linked immunosorbent assay confirmed the anticipated finding of naturally acquired antibodies to tetanus toxin both in humans and animals on the Galapagos Islands. In 57 inhabitants (mean age, 31.3 years) who had not been vaccinated against tetanus, antibody to tetanus toxin was detected in the blood by varying titers (geometric mean [reciprocal] titer [GMT], 0.015 international units [IU]/ml). In one individual the titer of antibody was > 12.5 IU/ml. Two individuals who had never been vaccinated against tetanus but who had reported having had clinical tetanus had titers of antibody to tetanus toxin of 0.02 IU/ml and 0.3 IU/ml, respectively. All nine of the animals studied showed antibody to tetanus toxin (GMT, 0.028 IU/ml).
dc.description.firstpage308
dc.description.issuenumber2
dc.description.lastpage311
dc.description.volume147
dc.identifier.doi10.1093/infdis/147.2.308
dc.identifier.issn0022-1899
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/38083
dc.relation.ispartofJournal of Infectious Diseases
dc.rightsAcesso Restrito
dc.titleNaturally acquired antibodies to tetanus toxin in humans and animals from the Galapagos Islands
dc.typeArtigo
local.scopus.citations24
local.scopus.eid2-s2.0-0020664181
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0020664181&origin=inward
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