Self-report of psychological symptoms in hypoparathyroidism patients on conventional therapy

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dc.contributor.authorArneiro A.J.
dc.contributor.authorDuarte B.C.C.
dc.contributor.authorKulchetscki R.M.
dc.contributor.authorCury V.B.S.
dc.contributor.authorLopes M.P.
dc.contributor.authorKliemann B.S.
dc.contributor.authorBini I.B.
dc.contributor.authorAssad M.A.
dc.contributor.authorBiagini G.L.K.
dc.contributor.authorBorba V.Z.C.
dc.contributor.authorMoreira C.A.
dc.date.accessioned2024-03-12T23:57:45Z
dc.date.available2024-03-12T23:57:45Z
dc.date.issued2018
dc.description.abstract© AE&M. All rights reserved.Objective: Hypoparathyroidism is characterized by parathyroid hormone deficiency and hypocalcemia. It has been demonstrated that these patients may also present psychiatric symptoms and decrease of quality of life. The aims of this study were to evaluate the presence of psychopathological symptoms in a cohort of patients with hypoparathyroidism and compare to a control group. Subjects and methods: Patients were submitted to a cross-sectional Symptom Checklist-90-R (SCL-90-R) questionnaire that evaluates psychopathological symptoms by means of the Global Severity Index (GSI), Positive Symptoms Total (PST) and Positive Symptom Distress Index (PSDI). A score based in the positive symptoms was calculated (T-score). The test group was composed of patients with hypoparathyroidism, and control by thyroidectomized patients without hypoparathyroidism. A correlation between the presence of psychological symptoms and clinical features was analyzed. Results: The study included 57 patients with a mean age of 51.1 ± 16.4 years; 20 as a control and 37, test group. There were no differences between groups regarding gender, mean age and age at diagnose. Hypoparathyroidism patients presented higher GSI index than the control group (p = 0.038). Mean T-score of the test group was as elevated as 58.2 ± 5.3 (reference range < 55). No correlation of the number of psychological symptoms to clinical and laboratorial parameters was observed. Conclusion: Patients with hypoparathyroidism attending our outpatient clinics presented an increase in the number of self-report of psychological symptoms when compared with a control group. However, no correlation with hypocalcemia and clinical parameters was observed. Future studies are necessary to evaluated if the absence of PTH play a role on it.
dc.description.firstpage319
dc.description.issuenumber3
dc.description.lastpage324
dc.description.volume62
dc.identifier.doi10.20945/2359-3997000000041
dc.identifier.issn2359-4292
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/35523
dc.relation.ispartofArchives of Endocrinology and Metabolism
dc.rightsAcesso Aberto
dc.subject.otherlanguageHypoparathyroidism
dc.subject.otherlanguageParathyroid hormone
dc.subject.otherlanguagePsychological distress
dc.subject.otherlanguagePsychopathological symptoms
dc.subject.otherlanguageSCL-90-R
dc.titleSelf-report of psychological symptoms in hypoparathyroidism patients on conventional therapy
dc.typeArtigo
local.scopus.citations11
local.scopus.eid2-s2.0-85050749005
local.scopus.subjectCase-Control Studies
local.scopus.subjectCohort Studies
local.scopus.subjectCross-Sectional Studies
local.scopus.subjectFemale
local.scopus.subjectHumans
local.scopus.subjectHypoparathyroidism
local.scopus.subjectMale
local.scopus.subjectMiddle Aged
local.scopus.subjectQuality of Life
local.scopus.subjectSelf Report
local.scopus.subjectSurveys and Questionnaires
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85050749005&origin=inward
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