Transcranial DC stimulation coupled with TENS for the treatment of chronic pain: A preliminary study

Página do item simplificado
dc.contributor.authorBoggio P.S.
dc.contributor.authorAmancio E.J.
dc.contributor.authorCorrea C.F.
dc.contributor.authorCecilio S.
dc.contributor.authorValasek C.
dc.contributor.authorBajwa Z.
dc.contributor.authorFreedman S.D.
dc.contributor.authorPascual-Leone A.
dc.contributor.authorEdwards D.J.
dc.contributor.authorFregni F.
dc.date.accessioned2024-03-13T01:36:03Z
dc.date.available2024-03-13T01:36:03Z
dc.date.issued2009
dc.description.abstractObjective: Based on evidence showing that electrical stimulation of the nervous system is an effective method to decrease chronic neurogenic pain, we aimed to investigate whether the combination of 2 methods of electrical stimulation-a method of peripheral stimulation [transcutaneous electrical nerve stimulation (TENS)] and a method of noninvasive brain stimulation [transcranial direct current stimulation (tDCS)]-induces greater pain reduction as compared with tDCS alone and sham stimulation. Methods: We performed a preliminary, randomized, sham-controlled, crossover, clinical study in which 8 patients were randomized to receive active tDCS/active TENS ("tDCS/TENS" group), active tDCS/sham TENS ("tDCS" group), and sham tDCS/sham TENS ("sham" group) stimulation. Assessments were performed immediately before and after each condition by a blinded rater. Results: The results showed that there was a significant difference in pain reduction across the conditions of stimulation (P=0.006). Post hoc tests showed significant pain reduction as compared with baseline after the tDCS/TENS condition [reduction by 36.5% (±10.7), P=0.004] and the tDCS condition [reduction by 15.5% (±4.9), P=0.014], but not after sham stimulation (P=0.35). In addition, tDCS/TENS induced greater pain reduction than tDCS (P=0.02). CONCLUSIONS: The results of this pilot study suggest that the combination of TENS with tDCS has a superior effect compared with tDCS alone. © 2009 by Lippincott Williams & Wilkins.
dc.description.firstpage691
dc.description.issuenumber8
dc.description.lastpage695
dc.description.volume25
dc.identifier.doi10.1097/AJP.0b013e3181af1414
dc.identifier.issn1536-5409
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37437
dc.relation.ispartofClinical Journal of Pain
dc.rightsAcesso Restrito
dc.subject.otherlanguageBrain polarization
dc.subject.otherlanguageBrain stimulation
dc.subject.otherlanguageCentral pain
dc.subject.otherlanguageChronic pain
dc.subject.otherlanguageTranscranial direct current stimulation
dc.subject.otherlanguageTranscutaneous electrical nerve stimulation
dc.titleTranscranial DC stimulation coupled with TENS for the treatment of chronic pain: A preliminary study
dc.typeArtigo
local.scopus.citations93
local.scopus.eid2-s2.0-70349682127
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70349682127&origin=inward
Arquivos
Coleções
Artigos de periódico