Non-invasive brain stimulation and computational models in post-stroke aphasic patients: Single session of transcranial magnetic stimulation and transcranial direct current stimulation. A randomized clinical trial

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dc.contributor.authordos Santos M.D.
dc.contributor.authorCavenaghi V.B.
dc.contributor.authorMac-Kay A.P.M.G.
dc.contributor.authorSerafim V.
dc.contributor.authorVenturi A.
dc.contributor.authorTruong D.Q.
dc.contributor.authorHuang Y.
dc.contributor.authorBoggio P.S.
dc.contributor.authorFregni F.
dc.contributor.authorSimis M.
dc.contributor.authorBikson M.
dc.contributor.authorGagliardi R.J.
dc.date.accessioned2024-03-13T00:48:42Z
dc.date.available2024-03-13T00:48:42Z
dc.date.issued2017
dc.description.abstract© 2017, Associacao Paulista de Medicina. All rights reserved.CONTEXT AND OBJECTIVE: Patients undergoing the same neuromodulation protocol may present different responses. Computational models may help in understanding such differences. The aims of this study were, firstly, to compare the performance of aphasic patients in naming tasks before and after one session of transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS) and sham, and analyze the results between these neuromodulation techniques; and secondly, through computational model on the cortex and surrounding tissues, to assess current flow distribution and responses among patients who received tDCS and presented different levels of results from naming tasks. DESIGN AND SETTING: Prospective, descriptive, qualitative and quantitative, double blind, randomized and placebo-controlled study conducted at Faculdade de Ciências Médicas da Santa Casa de São Paulo. METHODS: Patients with aphasia received one session of tDCS, TMS or sham stimulation. The time taken to name pictures and the response time were evaluated before and after neuromodulation. Selected patients from the first intervention underwent a computational model stimulation procedure that simulated tDCS. RESULTS: The results did not indicate any statistically significant differences from before to after the stimulation. The computational models showed different current flow distributions. CONCLUSIONS: The present study did not show any statistically significant difference between tDCS, TMS and sham stimulation regarding naming tasks. The patients’ responses to the computational model showed different patterns of current distribution.
dc.description.firstpage475
dc.description.issuenumber5
dc.description.lastpage480
dc.description.volume135
dc.identifier.doi10.1590/1516-3180.2016.0194060617
dc.identifier.issn1516-3180
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/35720
dc.relation.ispartofSao Paulo Medical Journal
dc.rightsAcesso Aberto
dc.subject.otherlanguageAphasia
dc.subject.otherlanguageSpeech disorders
dc.subject.otherlanguageStroke
dc.subject.otherlanguageTranscranial direct current stimulation
dc.subject.otherlanguageTranscranial magnetic stimulation
dc.titleNon-invasive brain stimulation and computational models in post-stroke aphasic patients: Single session of transcranial magnetic stimulation and transcranial direct current stimulation. A randomized clinical trial
dc.typeArtigo
local.scopus.citations25
local.scopus.eid2-s2.0-85037339598
local.scopus.subjectAdult
local.scopus.subjectAged
local.scopus.subjectAphasia
local.scopus.subjectDouble-Blind Method
local.scopus.subjectFemale
local.scopus.subjectHumans
local.scopus.subjectMale
local.scopus.subjectMiddle Aged
local.scopus.subjectProspective Studies
local.scopus.subjectStroke
local.scopus.subjectStroke Rehabilitation
local.scopus.subjectTranscranial Direct Current Stimulation
local.scopus.subjectTranscranial Magnetic Stimulation
local.scopus.subjectTreatment Outcome
local.scopus.subjectYoung Adult
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037339598&origin=inward
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