Spectrophotometric determination of zinc in pharmaceutical and biological samples with di-2-pyridyl ketone benzoylhydrazone: A simple, fast, accurate and sensitive method

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Data de publicação
2008
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Analytical Letters
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13
Autores
Vieira L.E.M.
Vieira F.P.
Avila-Terra L.H.S.
Gaubeur I.
Guekezian M.
Suarez-Iha M.E.V.
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A simple, fast, accurate, and sensitive spectrophotometric method was developed to determine zinc(II). This method is based on the reaction of Zn(II) with di-2-pyridyl ketone benzoylhydrazone (DPKBH), at pH=5.5 and 50% (v/v) ethanol. Beers law was obeyed in the range 0.020-1.82 μg mL-1 with a molar apsorptivity of 3.64×104 L mol-1 cm-1, and a detection limit (3δ) of 2.29 μg L-1. The action of some interfering ions was verified and the developed method applied to pharmaceutical and biological samples. The results were then compared with those obtained by using a flame atomic absorption technique. Copyright © Taylor & Francis Group, LLC.
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